DRUG OF THE DAY
doxycycline
Tetracycline-class antibiotic
Before opening the card, recall one use, one safety check and one counseling point.
Reveal the drug learning card
Names and formulations
- Doxycycline hyclate: generic oral tablet in the bound label
Verify the salt, strength, and dosage form. Administration instructions can differ among doxycycline products.
Common use
Treatment of selected susceptible infections, including certain tick-borne, atypical respiratory, sexually transmitted, and dermatologic infections.
Mechanism of action
Binds the bacterial 30S ribosomal subunit and inhibits protein synthesis; activity is generally bacteriostatic.
Important adverse effects and monitoring
- Can cause photosensitivity, esophageal irritation/ulceration, intracranial hypertension, and severe skin reactions.
- Tooth discoloration and effects on bone growth are class concerns during tooth development; specific severe infections may justify use despite age or pregnancy concerns.
- Monitor clinical response and adverse effects; avoid unnecessary use to reduce resistance.
Patient counseling
- Take with a full glass of water and remain upright; do not take immediately before bed.
- Use sun protection and separate from aluminum, calcium, magnesium, iron, or bismuth products according to product instructions.
Interaction to recognize
With: antacids, iron, calcium, magnesium, or bismuth
Why it matters: Chelation or binding can reduce doxycycline absorption.
Practical response: Separate administration using the interval in the dispensed product labeling or pharmacist instructions.
Check the original sources
- DailyMed — doxycycline hyclate tablet prescribing information
Sections: Clinical Pharmacology; Indications and Usage; Warnings; Information For Patients; Drug Interactions; Adverse Reactions. Source checked 2026-09-13.
Selected learning points; verify current labeling for the complete prescribing information.